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Immunogenicity and Safety of a Newly Developed Tetanus-Diphtheria Toxoid (Td) in Healthy Korean Adolescents: a Multi-center, Randomized, Double-blind, Active-Controlled Phase 3 Trial.

J Korean Med Sci · 2021 · PMC8688341 · PMID 34931494

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a decreasing trendno p-value reported
Despite a decreasing trend in the incidence of tetanus, approximately 80,000 cases were reported in 2017, of which 38,000 were fatal.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.