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De novo Prediction of Cell-Drug Sensitivities Using Deep Learning-based Graph Regularized Matrix Factorization.

Pac Symp Biocomput · 2022 · PMC8691529 · PMID 34890156

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a decreasing trendno p-value reported
We observed a decreasing trend (the blue curve) of drug sensitivity similarity from the low quantiles of Euclidean distance to the high quantiles of Euclidean distance in the drug embedding space using only chemical structure information.

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