Barely Significant
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Comparative Efficacy of Systemic Agents for Brain Metastases From Non-Small-Cell Lung Cancer With an EGFR Mutation/ALK Rearrangement: A Systematic Review and Network Meta-Analysis.

Front Oncol · 2021 · PMC8691653 · PMID 34950579

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a trend toward significanceno p-value reported
Among included treatments, first generation TKI (gefitinib) plus chemotherapy ranked first in improving overall survival (P score=0.91) and showed a trend toward significance (HR=0.72, 95%CI 0.40-1.27) ( Figure 2C ) ( Supplement C , Figure S4 ).

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