Bulk and Single-Cell Profiling of Breast Tumors Identifies TREM-1 as a Dominant Immune Suppressive Marker Associated With Poor Outcomes.

Front Oncol · 2021 · PMC8692779 · PMID 34956864

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highly significantno p-value reported

Moreover, included among the seven genes were the two well-characterized TREM-1 target genes, IL1B and CXCL8 (IL8), both of which showed a highly significant positive correlation with TREM1 expression in the MDACC-701 dataset (Pearson and Spearman correlations >0.6; see Supplemental Figure 1 ).

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