an increasing trendP < 0.10
2 , in vivo, the number of ISC per crypt showed an increasing trend on d 7 ( P < 0.10).
2 , in vivo, the number of ISC per crypt showed an increasing trend on d 7 ( P < 0.10).
Furthermore, spheroids on d 0 had more Ki67-positive cells and enteroendocrine cells ( P < 0.05) and showed a decreasing trend in the ISC and goblet cells ( P < 0.10).