Changes in gut microbiota associated with antibiotic use are extremely significant, because dysregulation of gut microbiota is associated with numerous abnormalities like inflammatory bowel disease (IBD) ( 6 ), obesity ( 7 ), non-alcoholic fatty liver disease ( 8 ), cardiovascular disease ( 9 ) and other conditions.
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Association of Antibiotic Alterations in Gut Microbiota With Decreased Osseointegration of an Intramedullary Nail in Mice With and Without Osteomyelitis.
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