Barely Significant
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Comparison of Time and Cost Savings Using Different Cost Methodologies for Patient-Specific Instrumentation vs Standard Referencing in Total Ankle Arthroplasty.

Foot Ankle Orthop · 2019 · PMC8697097 · PMID 35097347

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may not be significantno p-value reported
However, minor variations in both coronal and sagittal alignment may or may not be significant clinically with newer-generation prosthesis.

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