NAC at higher dose 20 mg/mL reduced the levels of IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-13, GM-CSF, INFγ, TNFα (all p = 0.035 to 0.002) with IL-1α ( p = 0.051) at borderline significance.
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<i>N</i>-Acetylcysteine in Mechanically Ventilated Rats with Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome: The Effect of Intravenous Dose on Oxidative Damage and Inflammation.
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The effect of low dose NAC on MDA was almost significant (NAC10 vs.