NK Cells Armed with Chimeric Antigen Receptors (CAR): Roadblocks to Successful Development.

Cells · 2021 · PMC8699535 · PMID 34943898

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highly significantno p-value reported

Concerning the positive effect of IL-15 on NK cell persistence, tumor infiltration, and functionality, a herpes simplex-1-based oncolytic virus expressing IL-15/IL-15Rα has resulted in highly significant anti-glioblastoma effects in combination with EGFR CAR NK cells [ 112 ].

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