highly significantp < 0.001
Zooming in on critical interferon response genes, the heatmaps and GEE analyses of their combined z-score ( Figure 4 a,b) showed that, despite heterogeneity in timing between individuals, there was a highly significant interferon-induced response already on d3 in the low-dose group ( p < 0.001), and on d9 and d6 for the no- and high-dose group, respectively.