The Electronic Medical Records and Genomics (eMERGE) Network’s [ 9 ] multi-center pilot of electronic health record (EHR)-based pre-emptive pharmacogenetics (PGx) of the following gene–drug pairs ( CYP2C19 /clopidogrel, CYP2C9 / VKORC1 /warfarin, and SLCO1B1 /simvastatin) [ 10 ] showed that patients prescribed warfarin within the CPIC dosing guideline range had a statistical trend toward faster time to first stable target international normalized ratio (INR) compared to a starting dose outside this range [ 11 ].
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The Contribution of Pharmacogenetic Drug Interactions to 90-Day Hospital Readmissions: Preliminary Results from a Real-World Healthcare System.
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