Similarly, while CD63 is a prominent marker of EVs, understanding of the full EV complexity has yet to be resolved, and the contribution of other EV types may be significant.
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The sentences
There were trends of decreasing CD63+ and CD63+/AO+ event rates in infected cells, but they failed to reach significance despite CM showing ~2-fold greater events ( Figure 5 C), driven by 100 nm and 200 nm sizes ( Figure 5 D).