The p value of 0.0001 shows a highly significant difference in drug release at different pH values (5 and 7.4) in both MTX-NPs and MTX-NPs loaded hydrogel, while less significant ( p < 0.05) correlation has been observed in pure drug solution at pH (5 and 7.4). 3.9.2.
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Development and In Vitro/In Vivo Evaluation of pH-Sensitive Polymeric Nanoparticles Loaded Hydrogel for the Management of Psoriasis.
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