The significance of differentially expressed genes was determined based on fold change (−2 to 2) and p -value (0.05), where higher fold change indicated a more strongly down- or upregulated gene with possibly significant implications in host physiology ( Supplementary Tables S1–S4 ).
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Single-Cell and Bulk RNASeq Profiling of COVID-19 Patients Reveal Immune and Inflammatory Mechanisms of Infection-Induced Organ Damage.
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