Neuron-Derived Estrogen-A Key Neuromodulator in Synaptic Function and Memory.

Int J Mol Sci · 2021 · PMC8706511 · PMID 34948039

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While the decrease in LTP amplitude was highly significant in both sexes, the decrease was greatest in ovariectomized female mice as compared to male mice (e.g., 91% decrease in ovariectomized females versus 57% decrease in males as compared to FLOX controls) [ 7 ].

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