Down-Regulation of Yeast Helicase Ded1 by Glucose Starvation or Heat-Shock Differentially Impairs Translation of Ded1-Dependent mRNAs.

Consistent with these findings, these 258 Ded1-hyperdependent mRNAs presented highly significant enrichments for mRNAs, showing TE reductions in response to heat-shock at 42 °C versus 30 °C, the DED1-IDRm mutation, and glucose starvation but lesser or no significant enrichment for mRNAs affected by heat-shock at 42 °C vs. 40 °C or by Rap, respectively ( Figure 4 C).

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