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2-Dodecyl-6-Methoxycyclohexa-2,5-Diene-1,4-Dione Ameliorates Diabetic Cognitive Impairment Through Inhibiting Hif3α and Apoptosis.

Front Pharmacol · 2021 · PMC8716628 · PMID 34975464

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a decreasing trendno p-value reported
Although p-α-synuclein (Ser129, 18, and 46 kDa), α-synuclein, and its oligomers protein levels showed a decreasing trend after DMDD treatment, there was no significant difference between db/db-vehicle and db/db-DMDD group. lncRNAs and mRNAs Expressed Profiles in the 2-Dodecyl-6-Methoxycyclohexa-2,5-Diene-1,4-Dione-Treated db/db Mice In order to reveal the underlying mechanisms and potential targets of DMDD treatment in db/db mice, we performed RNA array on db/db-vehicle ( n = 3) and db/db-DMDD ( n = 3) mice hippocampal samples to find the genes that changed after DMDD treatment.

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