Although some case-control studies have demonstrated that HIPEC combined with EPIC is associated with improved survival, an increasing trend toward performing CRS plus oxaliplatin-based HIPEC makes EPIC a less preferred option [ 46 , 49 ].
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Although some case-control studies have demonstrated that HIPEC combined with EPIC is associated with improved survival, an increasing trend toward performing CRS plus oxaliplatin-based HIPEC makes EPIC a less preferred option [ 46 , 49 ].