Patient-specific apparent diffusion maps used to model nutrient availability in degenerated intervertebral discs.

Although the model suggested an overall trend of increasing lactate content and acidity in the disc as it degenerated, this was not observed as the disc degenerated from grade 4 to 5 (Figure 5B and Table 5 ).

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For example, average glucose concentrations followed a decreasing trend that was more obvious in minimum glucose levels (Figure 5A ).

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