HPV16 E1 dysregulated cellular genes involved in cell proliferation and host DNA damage: A possible role in cervical carcinogenesis.

PLoS One · 2021 · PMC8717967 · PMID 34968392

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a decreasing trendp -value = 0.20not close (p > 0.1)

There was a decreasing trend ( p -value = 0.20) of apoptosis in cells treated with QVD-OPH compared to untreated cells, with a decrease in the mean percentage of apoptotic cells by 0.23% (pEGFP) and 2.42% (pEGFP-E1), thus suggesting that apoptosis plays only a part of HPV16 E1-mediated cell death.

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