Molecular surveillance of pneumococcal carriage following completion of immunization with the 13-valent pneumococcal conjugate vaccine administered in a 3 + 1 schedule.

Co-colonization with two or more serotypes of lytA -positive samples over increasing post booster PCV13 time intervals showed an increasing trend (χ 2 for trend P < 0.001); this was also the case among lytA - and SP2020-positve samples (χ 2 for trend P = 0.002) (Supplementary Table S2 ).

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