Prevotellaceae produces butyrate to alleviate PD-1/PD-L1 inhibitor-related cardiotoxicity via PPARα-CYP4X1 axis in colonic macrophages.

J Exp Clin Cancer Res · 2022 · PMC8722009 · PMID 34980222

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a decreasing trendno p-value reported

The food intake by the mice treated with the PD-1/PD-L1 inhibitor BMS-1 (5 and 10 mg/kg) showed a decreasing trend compared with the control, although there was no significant difference among the three groups (Fig. 1 A).

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