The Determinants of B Cell Receptor Signaling as Prototype Molecular Biomarkers of Leukemia.

Front Oncol · 2021 · PMC8724047 · PMID 34993136

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highly significantno p-value reported

Notably, the IGHV mutational status is a first-line molecular determinant or biomarker for prognosis and classification of CLL with highly significant differences in clinical behavior ( 30 , 31 ).

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