An ontogenic study of receptor mechanisms by which acute administration of low-doses of methamphetamine suppresses DOI-induced 5-HT_2A-receptor mediated head-twitch response in mice.

In the present study a two-way analysis of ANOVA (age × treatment) showed highly significant differences of age ( F 2, 78 = 43.43, p < 0.0001), treatment ( F 3, 78 = 61.01, p < 0.0001), and age × treatment interaction ( F 6, 78 = 8.706, p < 0.0001; Fig. 5 ).

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