Deep learning-based brain transcriptomic signatures associated with the neuropathological and clinical severity of Alzheimer's disease.

When correlating with pathological biomarkers, the SI showed strong correlations with all the measurements ( P ≤ 3.2e−6), with the weakest correlation observed for diffuse plaque, which was still highly significant ( P = 3.2e−6) ( Fig. 2C ).

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