The role of action potential changes in depolarization-induced failure of excitation contraction coupling in mouse skeletal muscle.

When extracellular K + was kept at 3.5 mM, the ΔF/F was stable over time, with a slight trend towards increasing ( Figure 2A and B , 1.16 at 7 min vs. initial value normalized to 1, p=0.07, n = 5 fibers).

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