In both the male and the female datasets, TGFB1 emerges as a highly significant upstream regulator ( p -value_males = 1.2E-14 and p -value_females = 1.7E-7), although with widely differing z-scores (males = −1.4 and females = 0.4), reflecting a more inconsistent quantitative profile of TGFB1-related proteins in females.
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The Urinary Proteomic Profile Implicates Key Regulators for Urologic Chronic Pelvic Pain Syndrome (UCPPS): A MAPP Research Network Study.
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