Barely Significant
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Associations between matrix metalloproteinase, tissue inhibitor of metalloproteinase and collagen expression levels in the adjacent rectal tissue of colorectal carcinoma patients.

Mol Clin Oncol · 2022 · PMC8739078 · PMID 35003739

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a positive trendno p-value reported
It was notable that by applying neoadjuvant therapy before surgical removal of the tumour a positive trend in the content of collagen in the rectal tissue after resection was attained.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.