Structural and Molecular Insight into Piperazine and Piperidine Derivatives as Histamine H<sub>3</sub> and Sigma-1 Receptor Antagonists with Promising Antinociceptive Properties.

ACS Chem Neurosci · 2022 · PMC8739840 · PMID 34908391

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more or less significantno p-value reported

First of all, almost all compounds (except 15 ) showed more or less significant affinity toward both sigma receptors with different binding affinities.

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