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HLA-SPREAD: a natural language processing based resource for curating HLA association from PubMed abstracts.

BMC Genomics · 2022 · PMC8740486 · PMID 34991484

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an increasing trendno p-value reported
Conclusion In summary, we collated all the HLA associations from the list of ~ 28 billion publicly available abstracts and observed review/associations with an increasing trend since 1975.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.