Potential Contribution of IL-27 and IL-23 Gene Polymorphisms to Multiple Sclerosis Susceptibility: An Association Analysis at Genotype and Haplotype Level.

J Clin Med · 2021 · PMC8745323 · PMID 35011777

Europe PMC DOI

hedged sentence

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

marginal significancep -value = 0.054so close (0.05 < p ≤ 0.1)

In the recessive genetic model, we found a marginal significance only for the association between smoking and IL-27- T4730C (Chi-square test, p -value = 0.054), the frequency of the variant CC genotype being higher in smokers (52.6%) than in non-smokers (30.4 %).

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