Novel Substituted Purine Isosteres: Synthesis, Structure-Activity Relationships and Cytotoxic Activity Evaluation.

Molecules · 2021 · PMC8746528 · PMID 35011476

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marginally non-significantno p-value reported

Compound 14b caused a statistically significant accumulation of PC-3 cells at G 2 /M phase, significantly reducing, in parallel, the percentage of cells at G 0 /G 1 phase (the accumulation of cells at S phase was marginally non-significant).

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