Growth Inhibition and Apoptotic Effect of Pine Extract and Abietic Acid on MCF-7 Breast Cancer Cells via Alteration of Multiple Gene Expressions Using In Vitro Approach.

Molecules · 2022 · PMC8746537 · PMID 35011526

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However, abietic acid showed markedly significant increases in gene expression levels after 24 h of Cyto-C, Bax , and p53 , which play important roles in intrinsic pathways with lower levels of Bcl-2 and a higher Bax/Bcl-2 ratio.

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