highly significantp < 0.01
× B+ 970.199 × C + 0.313121 × A × B + 15.5803 × A × B − 0.130687 × A × C + 0.237412 × A 2 − 0.00146488 × B 2 − 425.35 × C 2 Table 3 shows the ANOVA results of the quadratic regression model, from which it can be seen that the effect of the model on the swelling degree of the core–shell hydrogel is highly significant ( p < 0.01), and the experimental and predicted values are highly correlated (R 2 = 0.9810, R 2 adj = 0.9566), indicating that the model fits well experimentally and can be used to predict the optimal conditions for the swelling degree of the core–shell hydrogel.