Welfare Assessment, End-Point Refinement and the Effects of Non-Aversive Handling in C57BL/6 Mice with Lewis Lung Cancer.

Nest quality ( Figure 2 D) was largely the same in the cancer and control groups, but during the final 2 days, there was a more dramatic collapse in capability than in any of the other daily parameters, leading to a highly significant ‘Time’ by ‘Treatment’ interaction (F(8.504, 204.096) = 9.053, p < 0.001) (GG)).

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