CTCF Expression and Dynamic Motif Accessibility Modulates Epithelial-Mesenchymal Gene Expression.

As expected, there was a highly significant overlap between differentially expressed genes, either from CTCF overexpression ( Supplementary Figure S7A,B ) or CTCF knockdown ( Supplementary Figure S7C,D ) and genes nearby to CTCF binding motifs within accessible chromatin from untreated cells ( Supplementary Figure S7A,C ) or from cells treated with TGFβ for 10 days ( Supplementary Figure S7B,D ).

also in 132,142 other papers