Efficacy of Pitolisant 20 mg in Reducing Excessive Daytime Sleepiness and Fatigue in Patients with Obstructive Sleep Apnoea Syndrome: An Individual Patient Data Meta-analysis.

Clin Drug Investig · 2022 · PMC8755655 · PMID 34859394

Europe PMC DOI

hedged sentence

0.0010

closest p · 0.0× alpha

0.0010

boldest claim

The sentences

highly significantp < 0.001actually significant

Clinical Global Impression (CGI) A highly significant treatment effect was found on the CGI scale, with a benefit of − 0.63 (− 0.84; − 0.47; p < 0.001, Suppl. 9.2.1) compared with the placebo, confirmed by the results from the SMM model − 0.67 (− 0.97; − 0.36, p < 0.001, Suppl. 9.3, Fig. 1 ), and found to be homogeneous among studies.

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