Genomic features and tumor immune microenvironment alteration in NSCLC treated with neoadjuvant PD-1 blockade.

Further analysis of the number of genes with gain (CN value>3) or loss (CN value<1.5)-termed “CNgain” burden or “CNloss” burden, respectively-showed that CNgain burden (median = 8.5) had a more highly significant negative association with pathologic regression than TPS and CNA burden did ( R = −0.50, p = 0.02; Fig. 2a ).

also in 132,142 other papers