SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type 2 Pneumocytes, and Alveolar Macrophages of Smokers and COPD - Possible Implications for Interstitial Fibrosis.

Int J Chron Obstruct Pulmon Dis · 2022 · PMC8761078 · PMID 35046647

Europe PMC DOI

hedged sentences

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closest p · 2.0× alpha

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boldest claim

The sentences

near significancep = 0.1so close (0.05 < p ≤ 0.1)

In addition, ACE2 expressing AMs were also observed to significantly affect the small airway functionality FEF25–75% (r’= −0.30; p < 0.05) and near significance was seen for lung function parameter, FEV1/FVC% (r’= −0.22; p = 0.1).

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a decreasing trendno p-value reported

For ACE2 expression, compared to the COPD-CS group, the COPD-ES showed a decreasing trend, though this decline was not noticed for Furin and TMPRSS2 expression.

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