highly significantp < 2.2 × 10 −16
Subsequent statistical analysis revealed a highly significant ( p < 2.2 × 10 −16 ) cell cluster composition between the baseline sample NI Day + 0 ( n = 217 cells) compared to differentiated samples S Day + 15 ( n = 577 cells) and SON Day + 15 ( n = 400 cells) as well as between the differentiated samples ( Figure 3 C, Table S5 ).