Wild-type APC Influences the Severity of Familial Adenomatous Polyposis.

Cell Mol Gastroenterol Hepatol · 2022 · PMC8777002 · PMID 34774804

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highly significantP = 2.04e -23actually significant

Two hundred one APC 1311/+ pigs, representing 5 generations, were genotyped, revealing a highly significant correlation (Kruskal-Wallis test; P = 2.04e -23 ); pigs with A∗A genotype averaged 12 and with A∗G 107 polyps (last 40 cm of the colon) (interquartile range = 28.5 versus interquartile range = 138) ( Figure 1 C and D ).

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