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Implant-bone-interface: Reviewing the impact of titanium surface modifications on osteogenic processes in vitro and in vivo.

Bioeng Transl Med · 2022 · PMC8780039 · PMID 35079626

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highly significantno p-value reported
This indicates that the nano‐roughness of a surface is a highly significant factor for implant performance, which may be more significant than mimicking the bone micro‐scale.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.