Barely Significant
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Celecoxib-Loaded Solid Lipid Nanoparticles for Colon Delivery: Formulation Optimization and In Vitro Assessment of Anti-Cancer Activity.

Pharmaceutics · 2022 · PMC8780659 · PMID 35057027

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highly significantno p-value reported
F9 is regarded as the best SLN formulation because it combines all beneficial properties such as highly significant cytotoxic effects in three cancer cell lines, robust physical properties, uniform drug release, and the absence of components with potential adverse effects and toxicity.

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extremely significantno p-value reported
The anticancer activity of one formulation was extremely significant in all tested cancer cell lines at all incubation times, which is very promising. solid lipid nanoparticles ultrasonic melt-emulsification celecoxib HT29 MTT zeta-potential pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY 1.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.