highly significantp < 0.0001
By metaphase, statistically highly significant EBV-IS ( p < 0.0001) were located on 13q21 (33 metaphases); 19q13 and 22q12 (16 metaphases); 1p35, 2p23, 2q31, 7p22, and 13p11 (15 metaphases); 3q26 and 7q21 (13 metaphases); 2q21, 4q21, and 4q34 (12 metaphases); 15q14, and 17q25 (11 metaphases); as well as 1q31 and 12q21 (eight metaphases).