Impact of Inherited Genetic Variants on Critically Ill Septic Children.

Pathogens · 2022 · PMC8781648 · PMID 35056044

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might be significantno p-value reported

The reason is probably multifactorial and may include the direct effects of the invading microorganisms, their toxic products, release of proinflammatory mediators, complement activation and, in some individuals, genetic susceptibility to developing sepsis might be significant.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.