Managing Neovascular Age-Related Macular Degeneration in Clinical Practice: Systematic Review, Meta-Analysis, and Meta-Regression.

After imputing missing studies in the funnel plot, adjustment of effect size for possible publication bias using the trim-and-fill correction results in decreased, albeit still highly significant estimate of pooled mean difference (adjusted = +4.35 ETDRS letters; CI 95%: +4.02; +4.68; p < 0.0001).

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