Human papillomavirus persistence or clearance after infection in reproductive age. What is the status? Review of the literature and new data of a vaginal gel containing silicate dioxide, citric acid, and selenite.

According to statistical evaluation with Fisher’s exact test of independence, the association between treatment with vaginal gel and overall improvement of cytological findings was highly significant when compared to the non-treated group ( p < 0.0001). 41 In the same study, the clearance of high-risk HPV was assessed to evaluate the efficacy of the vaginal gel.

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