The influence of docetaxel schedule on treatment tolerability and efficacy in patients with metastatic breast cancer: a systematic review and meta-analysis of randomized controlled trials.

BMC Cancer · 2022 · PMC8788086 · PMID 35078455

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0500

boldest claim

The sentences

borderline significantp = 0.05actually significant

Meta-analysis of this outcome indicated a borderline significant association between increased risk of treatment discontinuation and the weekly schedule (RR 1.52, 95% CI: 1.00 – 2.32, p = 0.05).

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of borderline significanceno p-value reported

Although of borderline significance, this difference is important to note since it may affect the patient’s preference of docetaxel regimen and ultimately the outcome of docetaxel treatment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.