Pharmacology of enflicoxib, a new coxib drug: Efficacy and dose determination by clinical and pharmacokinetic-guided approach for the treatment of osteoarthritis in dogs based on an acute arthritis induction model.

Vet Med Sci · 2022 · PMC8788976 · PMID 34854245

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not yet significantno p-value reported

Although enflicoxib shows an evident in vitro COX‐2 inhibition activity, the MEC could not be determined in this analysis, as no evidence of efficacy was observed on the first day of treatment in the arthritis induction trials described above, when levels of pyrazol metabolite are not yet significant.

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