Dietary curcumin restores insulin homeostasis in diet-induced obese aged mice.

While HFHSD, as expected, caused a highly significant increase in FPI by 15 weeks compared to baseline (p < 0.01), in the HFHSD+CUR group this was much less (1.08 ± 0.49 vs. 1.53 ± 0.61 ng/mL; p = 0.14) than with HFHSD alone and was similar to that of the NCD group at that time ( Figure 4A ).

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